Formaldehyde → HCID 22766471, compound

HRID 1111572Notes

Reaction equation

HRID 1111572 reaction equation
C=O.C[C:4](C)(O)[C:5]#[N:6].[C:9]([NH:12][C:13]1([C:23]([O:25][CH2:26][CH3:27])=[O:24])[CH2:18][C:17]([CH3:20])([CH3:19])[NH:16][C:15]([CH3:22])([CH3:21])[CH2:14]1)(=[O:11])[CH3:10].[OH-].[Na+]>>[C:9]([NH:12][C:13]1([C:23]([O:25][CH2:26][CH3:27])=[O:24])[CH2:18][C:17]([CH3:20])([CH3:19])[N:16]([CH2:4][C:5]#[N:6])[C:15]([CH3:21])([CH3:22])[CH2:14]1)(=[O:11])[CH3:10]

Participants

5

Reactant 4

HCID 712FormaldehydeHCID 6406Acetone CyanohydrinHCID 14798Sodium HydroxideHCID 22766556HCID 22766556, compound

Product 1

HCID 22766471HCID 22766471, compound

Procedure

0.9 g of 37% formalin solution and 2 ml of acetone cyanohydrin were added to 1 g of 4-acetamido-4-ethoxycarbonyl-2,2,6,6-tetramethylpiperidine obtained by the procedure of Example 2. The resulting mixture was stirred at room temperature, 0.4 ml of 0.1 N-sodium hydroxide solution was added to it, and the mixture was then stirred at room temperature for 3 hours.

Workup

  1. customobtained by the procedure of Example 2
  2. stirringthe mixture was then stirred at room temperature for 3 hours

Sources & evidence

ORD record
ord-6a742620bcc443e596562e7c68b963fd
Source dataset
uspto-grants-1978_10
Patent number
US04118368

Reaction notes

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