Nitric Acid → HCID 20306119, compound

HRID 1111636Notes

Reaction equation

HRID 1111636 reaction equation
[N+:1]([O-:4])(O)=[O:2].[Cl:5][C:6]1[CH:11]=[C:10]([Cl:12])[CH:9]=[CH:8][C:7]=1[CH:13]([CH2:20][CH2:21][CH2:22][CH3:23])[CH2:14][N:15]1[CH:19]=[CH:18][N:17]=[CH:16]1.O>S(=O)(=O)(O)O>[Cl:5][C:6]1[CH:11]=[C:10]([Cl:12])[C:9]([N+:1]([O-:4])=[O:2])=[CH:8][C:7]=1[CH:13]([CH2:20][CH2:21][CH2:22][CH3:23])[CH2:14][N:15]1[CH:19]=[CH:18][N:17]=[CH:16]1

Participants

5

Reactant 3

HCID 944Nitric AcidHCID 962WaterHCID 30068521H-Imidazole, 1-[2-(2,4-dichlorophenyl)hexyl]-

Product 1

HCID 20306119HCID 20306119, compound

Reagents, catalysts & solvents 1

HCID 1118Sulfuric AcidSolvent2×

Procedure

To a solution of 40 ml of nitric acid and 10 ml of sulfuric acid, 14.8g (0.0498 mole) of 1-[β-(2,4-dichlorophenyl)hexyl]imidazole in 30 ml of sulfuric acid is added at less than 5°. The reaction is stirred for 1/2 hour and then it is poured into iced water. The oily solid which separates is isolated by decanting off the dilute acid solution. The residue is washed and then treated with ammonium hydroxide solution.

Workup

  1. customThe oily solid which separates is isolated
  2. customby decanting off the dilute acid solution
  3. washThe residue is washed
  4. additiontreated with ammonium hydroxide solution

Sources & evidence

ORD record
ord-33d2962a14574f28a916d74d5bb52483
Source dataset
uspto-grants-1978_10
Patent number
US04118461

Reaction notes

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