Methyl iodide → 1-methoxy-N,N-dimethyl-4-phenoxy-2-butanamine

HRID 1111694Notes

Reaction equation

[CH:1]([O:3][CH2:4][CH:5]([NH:15][CH:16]=O)[CH2:6][CH2:7][O:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)=O.[CH3:18]I>>[CH3:1][O:3][CH2:4][CH:5]([N:15]([CH3:16])[CH3:18])[CH2:6][CH2:7][O:8][C:9]1[CH:10]=[CH:11][CH:12]=[CH:13][CH:14]=1

Participants

Reactant 2

HCID 6328Methyl iodide

HCID 54572717HCID 54572717, compound

Product 1

HCID 227550141-methoxy-N,N-dimethyl-4-phenoxy-2-butanamine

Procedure

2-(formylamino)-4-phenoxy-1-butanol formate, described in Example 3, with methyl iodide, followed by reduction, gives 1-methoxy-N,N-dimethyl-4-phenoxy-2-butanamine,

Sources & evidence

ORD record: ord-6ae218ecc7bc4fc283eae4a29c857d1d
Source dataset: uspto-grants-1978_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04118511

Reaction notes

Loading…