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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 111170Generated: October 25, 2026

Water → 4-(9-cyclopentyl-7,7-difluoro-6-oxo-6,7,8,9-tetrahydro-5H-pyrimido[4,5-b][1,4]diazepin-2-ylamino)-N-(1-methyl-piperidin-4-yl)-benzamide

https://huagongshe.com/reaction/111170

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantIsopropanolHCID 3776—
Reactantp-Toluenesulfonic acidHCID 6101—
Reactant4-amino-N-(1-methylpiperidin-4-yl)benzamideHCID 43373280—
Reactant2-Chloro-9-cyclopentyl-7,7-difluoro-8,9-dihydro-5H-pyrimido[4,5-B][1,4]diazepin-6(7H)-oneHCID 57955611—
Product4-(9-cyclopentyl-7,7-difluoro-6-oxo-6,7,8,9-tetrahydro-5H-pyrimido[4,5-b][1,4]diazepin-2-ylamino)-N-(1-methyl-piperidin-4-yl)-benzamideHCID 58015148—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-3a33111158ba49e480ba89878236d36b
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)