Formaldehyde → HCID 54463956, compound

HRID 1111727Notes

Reaction equation

HRID 1111727 reaction equation
[CH:1]1([NH:4][C:5](=[S:13])[CH2:6][C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][N:8]=2)[CH2:3][CH2:2]1.[CH2:14]=O.[NH:16]1[CH2:21][CH2:20][O:19][CH2:18][CH2:17]1>CO>[CH:1]1([NH:4][C:5](=[S:13])[CH:6]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][N:8]=2)[CH2:14][N:16]2[CH2:21][CH2:20][O:19][CH2:18][CH2:17]2)[CH2:3][CH2:2]1

Participants

5

Reactant 3

HCID 712FormaldehydeHCID 8083MorpholineHCID 15581949HCID 15581949, compound

Product 1

HCID 54463956HCID 54463956, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

By the procedure of Example 2, N-cyclopropyl-2-(2-pyridyl)thioacetamide is reacted with formaldehyde and morpholine in methanol to give N-cyclopropyl-3-morpholino-2-(2-pyridyl)thiopropanamide.

Sources & evidence

ORD record
ord-2fdb35fb29164fb0958ef648a4909c81
Source dataset
uspto-grants-1978_10
Patent number
US04118567

Reaction notes

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