Dimethylformamide → HCID 131711288, compound

Participants

Reaction Steps

A mixture of 8.23 g of the product of Example 1 and 45.0 ml of dimethylformamide is warmed until solution is achieved. The solution is cooled to room temperature and 90.0 ml of 1N sodium hydroxide is added with stirring. The solution is stirred for 20 minutes and diluted with 250 ml of ethanol. The product is collected and washed with ethanol and ether to yield a pale yellow powder. The product is purified by a series of precipitations from 28.6% aqueous ethanol, then from 33.3% aqueous ethanol, and is dried to yield 1.67 g of the product of the Example as a pale yellow powder.

Provenance & Evidence