Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl L-phenylalaninate hydrochloride → N-benzyloxycarbonyl (beta-benzyl)-L-aspartyl-L-phenylalanine methyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl L-phenylalaninate hydrochloride | HCID 75736 | — |
| 반응물 | N-benzyloxycarbonyl-(beta-benzyl)-D,L-aspartic acid | HCID 18324139 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | N-benzyloxycarbonyl (beta-benzyl)-L-aspartyl-L-phenylalanine methyl ester | HCID 14876780 | 21.2% |
반응 단계
The process of Example 50 was repeated except that 715 mg (2.00 mmol) of N-benzyloxycarbonyl-(β-benzyl)-D,L-aspartic acid and 215 mg of L-phenylalanine methyl ester hydrochloride, 200 mg of Prolisin and 200 mg of the inhibitor were reacted. As a result, an 110 mg amount (yield of 21.2%) of N-benzyloxycarbonyl-(β-benzyl)-L-aspartyl-L-phenylalanine methyl ester having an [α]D22 = -12.8 (C=1.0 dimethylformamide) was obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04119493 |
| 출처 데이터셋 | uspto-grants-1978_10 |
| ORD ID | ord-b60f51b0bec14e00b7f28088e50fa530 |
| 출처 메모 | uspto-grants-1978_10 |