Sodium borohydride → HCID 22765892, compound

HRID 1111949Notes

Reaction equation

Cl.[NH2:2][C:3]1[C:8]([F:9])=[CH:7][C:6]([C:10](=[O:18])[CH2:11][N:12]([OH:17])[C:13]([CH3:16])([CH3:15])[CH3:14])=[CH:5][C:4]=1[Br:19].[BH4-].[Na+]>>[NH2:2][C:3]1[C:8]([F:9])=[CH:7][C:6]([CH:10]([OH:18])[CH2:11][N:12]([OH:17])[C:13]([CH3:16])([CH3:14])[CH3:15])=[CH:5][C:4]=1[Br:19]

Participants

Reactant 2

HCID 4311764Sodium borohydride

HCID 22765836HCID 22765836, compound

Product 1

HCID 22765892HCID 22765892, compound

Procedure

m.p. 122°-125° C., was prepared from 4'-amino-3'-bromo-5'-fluoro-2-(hydroxy-tert.butylamino)-acetophenone hydrochloride and sodium borohydride analogous to Example 1.

Sources & evidence

ORD record: ord-64092aeb79ca40edabcaef9e581d63b4
Source dataset: uspto-grants-1978_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04119710

Reaction notes

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