Sodium borohydride → HCID 13355629, compound

HRID 1111952Notes

Reaction equation

[NH2:1][C:2]1[C:7]([C:8]([F:11])([F:10])[F:9])=[CH:6][C:5]([C:12](=[O:18])[CH2:13][NH:14][CH:15]2[CH2:17][CH2:16]2)=[CH:4][C:3]=1[Cl:19].[BH4-].[Na+]>>[NH2:1][C:2]1[C:7]([C:8]([F:9])([F:10])[F:11])=[CH:6][C:5]([CH:12]([OH:18])[CH2:13][NH:14][CH:15]2[CH2:16][CH2:17]2)=[CH:4][C:3]=1[Cl:19]

Participants

Reactant 2

HCID 4311764Sodium borohydride

HCID 13355599HCID 13355599, compound

Product 1

HCID 13355629HCID 13355629, compound

Procedure

m.p. 138°-139° C., was prepared from 4'-amino-3'-chloro-2-cyclopropylamino-5'-trifluoromethyl-acetophenone and sodium borohydride analogous to Example 1.

Sources & evidence

ORD record: ord-1a565aecadc34dc684c2736442486d8f
Source dataset: uspto-grants-1978_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04119710

Reaction notes

Loading…