3-Amino-5,6-dimethyl-1,2,4-triazine → N-[(5,6-dimethyl-1,2,4-triazin-3-yl)aminocarbonyl]-2-chlorobenzenesulfonamide

HRID 1112039Notes

Reaction equation

HRID 1112039 reaction equation
[NH2:1][C:2]1[N:3]=[N:4][C:5]([CH3:9])=[C:6]([CH3:8])[N:7]=1.[Cl:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=1[S:17]([N:20]=[C:21]=[O:22])(=[O:19])=[O:18]>C(#N)C>[CH3:8][C:6]1[N:7]=[C:2]([NH:1][C:21]([NH:20][S:17]([C:12]2[CH:13]=[CH:14][CH:15]=[CH:16][C:11]=2[Cl:10])(=[O:18])=[O:19])=[O:22])[N:3]=[N:4][C:5]=1[CH3:9]

Participants

4

Reactant 2

HCID 871633-Amino-5,6-dimethyl-1,2,4-triazineHCID 174071Benzenesulfonyl isocyanate, 2-chloro-

Product 1

HCID 22764600N-[(5,6-dimethyl-1,2,4-triazin-3-yl)aminocarbonyl]-2-chlorobenzenesulfonamide

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

To a dry, well stirred mixture of 12 g of 3-amino-5,6-dimethyl-1,2,4-triazine in 100 ml of acetonitrile at ambient temperature and pressure was added 21 g of 2-chlorobenzenesulfonyl isocyanate. The mixture was stirred for 6 hours and the precipitated product removed by filtration. After washing with diethyl ether, the product melted at 142°-145°.

Workup

  1. customthe precipitated product removed by filtration
  2. washAfter washing with diethyl ether

Sources & evidence

ORD record
ord-8cdbf34ed9aa418fa1029466a05cb6eb
Source dataset
uspto-grants-1978_10
Patent number
US04120691

Reaction notes

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