反应详情

Still further, a mixture of 6,7-dimethoxy-2-aminoquinoline-3-carboxamide (0.5 g., 2 millimoles), ethyl cyanoformate (0.43 g., 44 millimiles) and benzene (30 ml.) is refluxed for three days. The mixture is then cooled, filtered and the solid extracted with chloroform. Concentration of the chloroform extract affords the product which is recrystallized from chloroform.

1. temperatureis refluxed for three days
2. temperatureThe mixture is then cooled
3. filtrationfiltered
4. extractionthe solid extracted with chloroform
5. extractionConcentration of the chloroform extract
6. customaffords the product which
7. customis recrystallized from chloroform