Veratraldehyde → HCID 70626058, compound

Participants

Reaction Steps

A solution of 5.0 g (0.025 mole) of the compound of Example I in a mixture of 13 ml of H2O and 20 ml of CH3OH was treated rapidly with a solution of 4.7 g (0.027 mole) of veratraldehyde in 40 ml of methanol using mechanical stirring. The reaction mixture was stirred rapidly for 0.8 hr and filtered. The yellow-brown solid was washed with 40 ml of methanol, ether and air dried, m.p. 232°-233°dec. yield: 7.2 g (83%). Recrystallization from methanol raised the melting point to 235°-236°, dec.

Provenance & Evidence