HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Acetate → cis-3-Azido-4-oxo-2-azetidinylmethyl bromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | Lithium Bromide | HCID 82050 | — |
| Reactant | HCID 86734335 | HCID 86734335 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | cis-3-Azido-4-oxo-2-azetidinylmethyl bromide | HCID 86736078 | — |
Reaction Steps
A degassed solution of cis-3-azido-4-oxo-2-azetidinylmethyl tosylate (0.41 g, 1.4 mmol) in dimethylformamide (5 ml) was heated to 90° with LiBr (0.43 g, 5 mmol) for 4 hours. The reaction was poured into ethyl acetate and washed copiously with water. The dried solution was evaporated to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04122086 |
| Source dataset | uspto-grants-1978_10 |
| ORD ID | ord-7f9dc7402b6f40cfba065dd4816442d6 |
| Source note | uspto-grants-1978_10 |