Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Benzyl-2-(chloromethyl)morpholine → 4-Benzyl-2-(1-phenyl-2,3-dihydro-imidazo(4,5-b)pyridin-2-on-3-yl-methyl)-morpholine hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Benzyl-2-(chloromethyl)morpholine | HCID 2801562 | — |
| 반응물 | 1-Phenyl-2,3-dihydroimidazo(4,5-b)pyridin-2-one | HCID 21321275 | — |
| 생성물 | 4-Benzyl-2-(1-phenyl-2,3-dihydro-imidazo(4,5-b)pyridin-2-on-3-yl-methyl)-morpholine hydrochloride | HCID 70601730 | 43.5% |
반응 단계
The condensation of 0.1 mol of 1-phenyl-2,3-dihydroimidazo(4,5-b)pyridin-2-one and of 0.1 mol of 2-chloromethyl-4-benzyl-morpholine is carried out in accordance with the procedure of Example 1. Recrystallization of the product from a 50/25 mixture of ethyl acetate and isopropanol gives 19 g of 4-benzyl-2-(1-phenyl-2,3-dihydroimidazo (4,5-b)pyridin- 2-on-3-yl-methyl)-morpholine hydrochloride, m.p. 214° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04122175 |
| 출처 데이터셋 | uspto-grants-1978_10 |
| ORD ID | ord-62090bd0097647f5bc9e0edb821c578a |
| 출처 메모 | uspto-grants-1978_10 |