Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2H-Benzimidazol-2-one, 1,3-dihydro-6-chloro-1-phenyl- → 4-Benzyl-2-(1-phenyl-6-chloro-2,3-dihydro-benzimidazol-2-on-3-yl-methyl)-morpholine hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2H-Benzimidazol-2-one, 1,3-dihydro-6-chloro-1-phenyl- | HCID 108653 | — |
| 반응물 | 4-Benzyl-2-(chloromethyl)morpholine | HCID 2801562 | — |
| 생성물 | 4-Benzyl-2-(1-phenyl-6-chloro-2,3-dihydro-benzimidazol-2-on-3-yl-methyl)-morpholine hydrochloride | HCID 70601802 | — |
반응 단계
The condensation of 0.1 mol of 1-phenyl-6-chloro-2,3-dihydro-benzimidazol-2-one and 0.1 mol of 2-chloromethyl-4-benzyl-morpholine is carried out in accordance with the procedure of Example 1. By washing the product with hot acetone, 28 g of 4-benzyl-2-(1-phenyl-6-chloro-2,3-dihydrobenzimidazol-2-on-3-yl-methyl)-morpholine hydrochloride are obtained, m.p. 185° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04122175 |
| 출처 데이터셋 | uspto-grants-1978_10 |
| ORD ID | ord-0d1f9d44c76945d68ac60e26bdeb17e3 |
| 출처 메모 | uspto-grants-1978_10 |