Vincamine → Vincamine furoate

HRID 1112364Notes

Reaction equation

HRID 1112364 reaction equation
[CH3:1][CH2:2][C@:3]12[CH2:19][C@:18]([OH:24])([C:20]([O:22][CH3:23])=[O:21])[N:17]3[C:9]4=[C:10]([CH2:25][CH2:26][N:7]([C@@H:8]14)[CH2:6][CH2:5][CH2:4]2)[C:11]1[CH:12]=[CH:13][CH:14]=[CH:15][C:16]=13>O>[CH3:1][CH2:2][C@:3]12[CH2:19][C@:18]([OH:24])([C:20]([O:22][CH3:23])=[O:21])[N:17]3[C:9]4=[C:10]([CH2:25][CH2:26][N:7]([C@@H:8]14)[CH2:6][CH2:5][CH2:4]2)[C:11]1[CH:12]=[CH:13][CH:14]=[CH:15][C:16]=13.[O:24]1[CH:2]=[CH:3][CH:19]=[C:18]1[C:20]([O-:22])=[O:21]

Participants

3

Reactant 1

HCID 15376Vincamine

Product 1

HCID 131711313Vincamine furoate

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

The reaction mixture is then concentrated to a dry residue, and the product is ground and dried in an aerated furnace. There are obtained 9.3 g of a substance, insoluble in water and alcohol, having a vincamine content of 74%.

Workup

  1. concentrationThe reaction mixture is then concentrated to a dry residue
  2. customdried in an aerated furnace
  3. customThere are obtained 9.3 g of a substance

Sources & evidence

ORD record
ord-f16c735559314107916bfa569ee6f54c
Source dataset
uspto-grants-1978_10
Patent number
US04122179

Reaction notes

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