HRID1112371

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC[C@]12CCCN3CCc4c(n(c5ccccc45)[C@@](O)(C(=O)OC)C1)[C@@H]32

HCID15376

Vincamine

C21H26N2O3

HCID69550

Acefylline

C9H10N4O4

PRODUCTS

生成物

结构：CC[C@]12CCCN3CCc4c(n(c5ccccc45)[C@@](O)(C(=O)OC)C1)[C@@H]32.Cn1c(=O)c2c(ncn2CC(=O)[O-])n(C)c1=O

HCID86736094

未命名化合物

PROCEDURE

实验过程

The salt is prepared, likewise the preceding examples, from 7.08 g (2.10-2 moles) of vincamine and 4.77 g (2.10-2 moles) of theophylline-7-acetic acid. There are obtained 12 g of a crystalline product having melting point of 188° C., which is soluble in alcohol and insoluble in water and in the common organic solvents.

WORKUP

后处理

customThe salt is prepared

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-fd736ba06c4544d6ba3191fc1640e2e0
来源数据集: uspto-grants-1978_10
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04122179
来源说明: uspto-grants-1978_10

反应 SMILES

[CH3:1][CH2:2][C@:3]12[CH2:19][C@:18]([OH:24])([C:20]([O:22][CH3:23])=[O:21])[N:17]3[C:9]4=[C:10]([CH2:25][CH2:26][N:7]([C@@H:8]14)[CH2:6][CH2:5][CH2:4]2)[C:11]1[CH:12]=[CH:13][CH:14]=[CH:15][C:16]=13.[N:27]1([C:38](=[O:39])[C:37]2[N:36]([CH2:40][C:41]([OH:43])=[O:42])[CH:35]=[N:34][C:33]=2[N:31]([CH3:32])[C:29]1=[O:30])[CH3:28]>>[CH3:1][CH2:2][C@:3]12[CH2:19][C@:18]([OH:24])([C:20]([O:22][CH3:23])=[O:21])[N:17]3[C:9]4=[C:10]([CH2:25][CH2:26][N:7]([C@@H:8]14)[CH2:6][CH2:5][CH2:4]2)[C:11]1[CH:12]=[CH:13][CH:14]=[CH:15][C:16]=13.[N:27]1([C:38](=[O:39])[C:37]2[N:36]([CH2:40][C:41]([O-:43])=[O:42])[CH:35]=[N:34][C:33]=2[N:31]([CH3:32])[C:29]1=[O:30])[CH3:28]