Hexanoic Acid → Vincamine caproate

HRID 1112372Notes

Reaction equation

HRID 1112372 reaction equation
[CH3:1][CH2:2][C@:3]12[CH2:19][C@:18]([OH:24])([C:20]([O:22][CH3:23])=[O:21])[N:17]3[C:9]4=[C:10]([CH2:25][CH2:26][N:7]([C@@H:8]14)[CH2:6][CH2:5][CH2:4]2)[C:11]1[CH:12]=[CH:13][CH:14]=[CH:15][C:16]=13.[C:27]([OH:34])(=[O:33])[CH2:28][CH2:29][CH2:30][CH2:31][CH3:32]>O>[CH3:1][CH2:2][C@:3]12[CH2:19][C@:18]([OH:24])([C:20]([O:22][CH3:23])=[O:21])[N:17]3[C:9]4=[C:10]([CH2:25][CH2:26][N:7]([C@@H:8]14)[CH2:6][CH2:5][CH2:4]2)[C:11]1[CH:12]=[CH:13][CH:14]=[CH:15][C:16]=13.[C:27]([O-:34])(=[O:33])[CH2:28][CH2:29][CH2:30][CH2:31][CH3:32]

Participants

4

Reactant 2

HCID 8892Hexanoic AcidHCID 15376Vincamine2×

Product 1

HCID 86736095Vincamine caproate

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

7.08 g (2.10-2 moles) of vincamine and 2.32 g (2.10-2 moles) of caproic acid are reacted according to the same method of the preceding example. There are obtained 8.2 g of an oily substance, insoluble in water and in the common solvents. The vincamine content is 67%.

Workup

  1. customThere are obtained 8.2 g of an oily substance

Sources & evidence

ORD record
ord-14a3c5c29356400aaf94b37b6bddb6d0
Source dataset
uspto-grants-1978_10
Patent number
US04122179

Reaction notes

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