Ammonium Chloride → HCID 70587015, compound

Participants

Reaction Steps

To a mixture of 27.8 g (0.1 mole) of 4-decyloxybenzoic acid and 300 ml of anhydrous ether stirred at room temperature is slowly added with stirring 100 ml of 2 M methyllithium in ether. The reaction mixture is stirred at room temperature for 2 hours then poured into 1 liter of a saturated ammonium chloride solution. The organic layer is separated, washed with 5% sodium bicarbonate and brine and evaporated to dryness to give a low melting solid which is recrystallized from hexane to give methyl 1-(4-decyloxy)phenyl ketone, M.P. 38°-39° C.

Provenance & Evidence