HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylamine → 2,3-dimethoxy N,N-dimethyl 6-hydroxymethyl benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylamine | HCID 674 | — |
| Reactant | Meconin | HCID 68437 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2,3-dimethoxy N,N-dimethyl 6-hydroxymethyl benzamide | HCID 22764030 | 100% |
Reaction Steps
A mixture of 30 g of 6,7-dimethoxy 3H-isobenzofuranone, prepared according to the method described in Example IV, 1 liter of ethanol and 300-400 cm3 of dimethylamine was agitated for several hours and then evaporated under vacuum at 30° - 35° C. The crystallized product was washed with heptane. The 2,3-dimethoxy N,N-dimethyl 6-hydroxymethyl benzamide was obtained in a yield of 100%. F = 90° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04122202 |
| Source dataset | uspto-grants-1978_10 |
| ORD ID | ord-873d25c134824e72a3a75654d0a7fb1c |
| Source note | uspto-grants-1978_10 |