HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium borohydride → N-[[2-[2-(4-Morpholinyl)ethoxy]phenyl]methyl]benzeneethanamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | N-[[2-[2-(4-Morpholinyl)ethoxy]phenyl]methylene]benzeneethanamine | HCID 21322775 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | N-[[2-[2-(4-Morpholinyl)ethoxy]phenyl]methyl]benzeneethanamine | HCID 21322749 | 78.4% |
Reaction Steps
N-[[2-[2-(4-Morpholinyl)ethoxy]phenyl]methylene]benzeneethanamine (68.5 g) is reduced with 22.5 g of sodium borohydride in 350 ml of methanol following the procedure described in Example 1B to yield 54 g of product as an oil, boiling point 216°-220° C at 0.2-0.3 mm of Hg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04122255 |
| Source dataset | uspto-grants-1978_10 |
| ORD ID | ord-953828f7ac9f42f8b9cb483ed0f45934 |
| Source note | uspto-grants-1978_10 |