2,5-Dichlorobenzyl chloride → 2-[2'-(2",5"-Dichlorobenzylthio)-5'-chlorophenyl]-imidazoline hydrochloride

HRID 1112469Notes

Reaction equation

HRID 1112469 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[S:13][C:8]3([NH:12][CH2:11][CH2:10][NH:9]3)[C:6]=2[CH:7]=1.[Cl:14][C:15]1[CH:22]=[CH:21][C:20]([Cl:23])=[CH:19][C:16]=1[CH2:17]Cl>CO>[ClH:1].[Cl:14][C:15]1[CH:22]=[CH:21][C:20]([Cl:23])=[CH:19][C:16]=1[CH2:17][S:13][C:5]1[CH:4]=[CH:3][C:2]([Cl:1])=[CH:7][C:6]=1[C:8]1[NH:12][CH2:11][CH2:10][N:9]=1

Participants

4

Reactant 2

HCID 759762,5-Dichlorobenzyl chlorideHCID 704691194-Chlorobenzothietane-2-spiro-2'-imidazoline

Product 1

HCID 704694202-[2'-(2",5"-Dichlorobenzylthio)-5'-chlorophenyl]-imidazoline hydrochloride

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

32 Parts of 4-chlorobenzothietane-2-spiro-2'-imidazolidine is reacted as described in Example 11 with 29.5 parts of 2,5-dichlorobenzyl chloride in 300 parts of methanol. The yield is 53 parts (86% of theory) and the melting point is 260° C. with decomposition.

Sources & evidence

ORD record
ord-d538dd92fe3d4c39a7f7890ce3b6e3dc
Source dataset
uspto-grants-1978_10
Patent number
US04122263

Reaction notes

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