HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl (5-ethyl-2-pyridyl)carbamate → 5-Ethylpyridin-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl (5-ethyl-2-pyridyl)carbamate | HCID 54145659 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 5-Ethylpyridin-2-amine | HCID 9812777 | 99.4% |
Reaction Steps
A suspension of benzyl (5-ethyl-2-pyridyl)carbamate (1.9 g., 7.43 mmoles) and 10% palladium-on-carbon (0.4 g.) in ethanol (100 ml.) was shaken with hydrogen at a pressure of 3.5 kg./cm2 hours. The catalyst was removed by filtration and the filtrate concentrated to yield 2-amino-5-ethylpyridine (0.9 g., 99.4%) as a colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04122274 |
| Source dataset | uspto-grants-1978_10 |
| ORD ID | ord-ac0f045daa7d4200962ce497ca19bbeb |
| Source note | uspto-grants-1978_10 |