HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 2-cyano-3-(5-ethyl-2-pyridylamino)acrylate → 7-Ethyl-3-(1H-tetrazol-5-yl)-4H-pyrido[1,2-a]pyrimidin-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 2-cyano-3-(5-ethyl-2-pyridylamino)acrylate | HCID 70593660 | — |
| Reactant | HCID 178515422 | HCID 178515422 | — |
| Product | 7-Ethyl-3-(1H-tetrazol-5-yl)-4H-pyrido[1,2-a]pyrimidin-4-one | HCID 178435573 | 28% |
Reaction Steps
The title compound (28% yield, m.p. 289°-290.5° with decomposition) was prepared from ethyl 2-cyano-3-(5-ethyl-2-pyridylamino)acrylate in a manner similar to that described for the preparation of 3-(1H-tetrazol-5-yl)-4H-pyrido[1,2-a]pyrimidin-4-one in Example 2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04122274 |
| Source dataset | uspto-grants-1978_10 |
| ORD ID | ord-2b7f6a16abee4407b194a2ef8b02d64c |
| Source note | uspto-grants-1978_10 |