2-Piperidino-4-imino-2-thiazoline hydrochloride → HCID 178421562, compound
Reaction equation
[CH3:1][C:2]1[C:10]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)=[C:9]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[C:8]([C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)=[C:7]2[C:3]=1[C:4](=N)[NH:5][C:6]2=[NH:29].[ClH:31].[CH2:32]([NH:39][C:40]1[S:41][CH2:42][C:43](=[NH:45])[N:44]=1)[C:33]1[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=1.N=C1C2C(=CC=CC=2)C(=N)N1.Cl.N1(C2SCC(=N)N=2)CCCCC1>>[ClH:31].[NH:29]=[C:6]1[C:7]2[C:3](=[C:2]([CH3:1])[C:10]([C:11]3[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=3)=[C:9]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)[C:8]=2[C:23]2[CH:24]=[CH:25][CH:26]=[CH:27][CH:28]=2)[C:4](=[C:42]2[S:41][C:40]([NH:39][CH2:32][C:33]3[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=3)=[N:44][C:43]2=[NH:45])[NH:5]1Participants
5
Procedure
Using a procedure similar to that described in Example 9, part B above but substituting 4-methyl-5,6,7-triphenyl-1,3-diiminoisoindoline and 2-benzylamino-4-imino-2-thiazoline hydrochloride for the 1,3-diiminoisoindoline and 2-piperidino-4-imino-2-thiazoline hydrochloride respectively, there is obtained as the product 1-imino-4-methyl-5,6,7-triphenyl-3-(2-benzylamino-4-imino-2-thiazolin-5-ylidene)isoindoline hydrochloride.
Sources & evidence
- ORD record
- ord-6c661982ef9a4bf8bbb3bd899af493de
- Source dataset
- uspto-grants-1978_10
- Patent number
- US04122261
Reaction notes
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