Acetone → HCID 86736123, compound

Participants

Reaction Conditions

Reaction Steps

A 3.3 g (0.028 mol) sample of methylsulfonyl chloride was added slowly to a slurry of 6.5 g (0.027 mol) of the sodium salt of alpha-cyano-2,6-dichlorobenzaldoxime in 60 ml acetone. The reaction was exothermic. After the addition was completed, the reaction mixture was stirred at about 25° C. for 1 hour, filtered and evaporated under reduced pressure to give a tan oil which crystallized to give the product. Recrystallization from ether/hexane gave the product as white crystals, m.p. 81-82. Nuclear magnetic resonance analysis showed the product to be approximately a 60:40 mixture of the syn- and anti-isomers. Elemental analysis for the product is tabulated in Table I as Compound No 3.

Provenance & Evidence