Hydrazine, (4-chlorophenyl)-, hydrochloride (1:1) → 2-(4-Chloro-2-fluorophenyl)-1,2,4,5,6,7-hexahydro-3H-indazol-3-one

HRID 1112577Notes

Reaction equation

HRID 1112577 reaction equation
Cl.ClC1C=CC(NN)=CC=1.Cl.[Cl:12][C:13]1[CH:18]=[CH:17][C:16]([NH:19][NH2:20])=[C:15]([F:21])[CH:14]=1.ClC1C=CC(N2[C:37](=[O:38])[C:36]3[CH2:35][CH2:34][CH2:33][CH2:32][C:31]=3N2)=CC=1>>[Cl:12][C:13]1[CH:18]=[CH:17][C:16]([N:19]2[C:37](=[O:38])[C:36]3[CH2:35][CH2:34][CH2:33][CH2:32][C:31]=3[NH:20]2)=[C:15]([F:21])[CH:14]=1

Participants

4

Reactant 3

HCID 71600Hydrazine, (4-chlorophenyl)-, hydrochloride (1:1)HCID 2782933(4-Chloro-2-fluorophenyl)hydrazine hydrochlorideHCID 164906132-(4-chlorophenyl)-4,5,6,7-tetrahydro-2H-indazol-3-ol

Product 1

HCID 227482812-(4-Chloro-2-fluorophenyl)-1,2,4,5,6,7-hexahydro-3H-indazol-3-one

Procedure

By substituting 4-chlorophenylhydrazine hydrochloride in the above procedure for 4-chloro-2-fluorophenylhydrazine hydrochloride, 2-(4-chlorophenyl)-1,2,4,5,6,7-hexahydro-3H-indazol-3-one was prepared, m.p. 183.5°-185° (Lit 186°-187°, Chem. Abs., 67, 11452h).

Workup

  1. customwas prepared

Sources & evidence

ORD record
ord-0f9580a96fac4bd7a363419c69a5a037
Source dataset
uspto-grants-1978_10
Patent number
US04123252

Reaction notes

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