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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1112588Generated: November 2, 2026

1-(4-methoxybenzyl)-1H-tetrazole-5-carbonyl chloride → 1-(4-methoxybenzyl)-N-[2-cyano-3-(2-methyl-4-morpholinyl)phenyl]-1H-tetrazole-5-carboxamide

https://huagongshe.com/reaction/1112588

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-methoxybenzyl)-1H-tetrazole-5-carbonyl chlorideHCID 20463870—
Reactant2-Amino-6-(2-methyl-4-morpholinyl)benzonitrileHCID 22756805—
Product1-(4-methoxybenzyl)-N-[2-cyano-3-(2-methyl-4-morpholinyl)phenyl]-1H-tetrazole-5-carboxamideHCID 22756797—

Reaction Steps

In a manner similar to Example I, 1-(4-methoxybenzyl)-1H-tetrazole-5-carbonyl chloride is condensed with 2-amino-6-(2-methyl-4-morpholinyl)benzonitrile to give 1-(4-methoxybenzyl)-N-[2-cyano-3-(2-methyl-4-morpholinyl)phenyl]-1H-tetrazole-5-carboxamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04123432
Source datasetuspto-grants-1978_10
ORD IDord-bf9d7fe4704a41739da7261a9feb9a5b
Source noteuspto-grants-1978_10