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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 111259Generated: October 26, 2026

Water → Tert-butyl 4-((5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)piperidine-1-carboxylate

https://huagongshe.com/reaction/111259

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantTetrahydrofuranHCID 8028—
Reactant18-Crown-6HCID 28557—
ReactantTert-butyl 4-hydroxypiperidine-1-carboxylateHCID 643502—
ReactantPotassiumHCID 5462222—
ReactantButan-1-olateHCID 12476378—
Reactant4-(Bromomethyl)-5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazoleHCID 59369328—
ProductTert-butyl 4-((5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)piperidine-1-carboxylateHCID 59369325—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-fb849cd46e384b96a5ab2fb945f3e24b
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)