HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloroacetic Acid → HCID 12893255, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloroacetic Acid | HCID 300 | — |
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | Sodium Bromide | HCID 253881 | — |
| Reactant | 3-Bromo-2-nitrobutan-1-ol | HCID 22762403 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 12893255 | HCID 12893255 | 91.3% |
Reaction Steps
94.5g (1 mol) of chloroacetic acid, 132.6g (1.3 mol) of sodium bromide, 127.4g (1.3 mol) of c.-sulfuric acid, 100 ml of water, 198g (1 mol) of 2-nitro-3-bromo-n-butanol and 200g of toluene were used and treated in a similar way as described in Example 10. 291.2g of 2-nitro-3-bromo-n-butyl bromoacetate were obtained (91.3% yield of theory). Bp 130° C/ 0.3 mmHg, nD20 = 1.5060, D420 = 1.7876. 175g (98.9%) of potassium hydrogen sulfate was isolated.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04123443 |
| Source dataset | uspto-grants-1978_10 |
| ORD ID | ord-367ed966198d41c3a2537de6cc6e4484 |
| Source note | uspto-grants-1978_10 |