Nitric Acid → HCID 70626110, compound

HRID 1112774Notes

Reaction equation

HRID 1112774 reaction equation
[N+:1]([O-:4])([OH:3])=[O:2].[Cl:5][C:6]1[CH:11]=[C:10]([Cl:12])[CH:9]=[CH:8][C:7]=1[S:13][C:14]([CH3:30])([CH2:21][CH2:22][C:23]1[CH:28]=[CH:27][C:26]([Cl:29])=[CH:25][CH:24]=1)[CH2:15][N:16]1[CH:20]=[CH:19][N:18]=[CH:17]1>>[N+:1]([O-:4])([OH:3])=[O:2].[Cl:5][C:6]1[CH:11]=[C:10]([Cl:12])[CH:9]=[CH:8][C:7]=1[S:13][C:14]([CH3:30])([CH2:21][CH2:22][C:23]1[CH:24]=[CH:25][C:26]([Cl:29])=[CH:27][CH:28]=1)[CH2:15][N:16]1[CH:20]=[CH:19][N:18]=[CH:17]1

Participants

3

Reactant 2

HCID 944Nitric AcidHCID 22762789HCID 22762789, compound

Product 1

HCID 70626110HCID 70626110, compound

Procedure

Nitric acid (70%; d=1.42) is added dropwise to a stirred solution of 2.0g. of 1-[2-(2,4-dichlorophenylthio)-2-methyl-4-(4-chlorophenyl)-n-butyl]imidazole in 200 ml. of anhydrous ether until precipitation is complete. The product is filtered off, washed with ether, air dried, and recrystallized from acetone/ethyl acetate to yield 1-[2-(2,4-dichlorophenylthio)-2-methyl-4-(4-chlorophenyl)-n-butyl]imidazole nitrate, m.p. 126.5°-128° C.

Workup

  1. customof anhydrous ether until precipitation
  2. filtrationThe product is filtered off
  3. washwashed with ether, air
  4. customdried
  5. customrecrystallized from acetone/ethyl acetate

Sources & evidence

ORD record
ord-6b49c37c3a8d44bfa7f80643b96cd973
Source dataset
uspto-grants-1978_10
Patent number
US04123542

Reaction notes

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