6-fluoro-3-(4-{4-[(2-methylpyridin-3-yl)oxy]phenyl}-1H-1,2,3-triazol-1-yl)-1-(2,2,2-trifluoroethyl)-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one → 3-(4-{4-[(2,6-dimethylpyridin-4-yl)oxy]phenyl}-1H-1,2,3-triazol-1-yl)-6-fluoro-1-(2,2,2-trifluoroethyl)-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one
Reaction equation
[CH3:38][c:39]1[n:40][c:41]([CH3:46])[cH:42][c:43]([OH:45])[cH:44]1.[F:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[c:7]1[CH2:8][CH2:9][CH:10]([n:19]1[n:20][n:21][c:22](-[c:24]3[cH:25][cH:26][c:27]([O:30][c:31]4[c:32]([CH3:33])[n:34][cH:35][cH:36][cH:37]4)[cH:28][cH:29]3)[cH:23]1)[C:11](=[O:18])[N:12]2[CH2:13][C:14]([F:15])([F:16])[F:17]>>[F:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[c:7]1[CH2:8][CH2:9][CH:10]([n:19]1[n:20][n:21][c:22](-[c:24]3[cH:25][cH:26][c:27]([O:30][c:43]4[cH:42][c:41]([CH3:46])[n:40][c:39]([CH3:38])[cH:44]4)[cH:28][cH:29]3)[cH:23]1)[C:11](=[O:18])[N:12]2[CH2:13][C:14]([F:15])([F:16])[F:17]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-b6f1f61696f74054b8589a853c83461e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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