Dichloromethane → 8-Chloro-4-[3-(4-chloromethyl-thiazol-2-yl)-phenyl]-7-dimethylamino-1,3-dihydro-benzo[b][1,4]diazepin-2-one
Reaction equation
[Cl:1][c:2]1[c:3]([N:27]([CH3:28])[CH3:29])[cH:4][c:5]2[c:6]([cH:26]1)[NH:7][C:8](=[O:25])[CH2:9][C:10]([c:12]1[cH:13][c:14](-[c:18]3[s:19][cH:20][c:21]([CH2:23][OH:24])[n:22]3)[cH:15][cH:16][cH:17]1)=[N:11]2.[Cl:34][CH2:35][Cl:36].[S:30]([Cl:31])([Cl:32])=[O:33]>>[Cl:1][c:2]1[c:3]([N:27]([CH3:28])[CH3:29])[cH:4][c:5]2[c:6]([cH:26]1)[NH:7][C:8](=[O:25])[CH2:9][C:10]([c:12]1[cH:13][c:14](-[c:18]3[s:19][cH:20][c:21]([CH2:23][Cl:32])[n:22]3)[cH:15][cH:16][cH:17]1)=[N:11]2Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-6e9ec6e696d848229f0d5dd5985efefd
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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