4-(Trifluoromethoxy)phenylboronic acid → 3-Hydroxy-1-[6-(4-trifluoromethoxy-phenyl)-pyridin-3-ylmethyl]-1H-thieno[3,2-d]pyrimidine-2,4-dione

HRID 1112987Notes

Reaction equation

HRID 1112987 reaction equation
[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH2:8][n:9]2[c:10](=[O:20])[n:11]([OH:19])[c:12](=[O:18])[c:13]3[c:14]2[cH:15][cH:16][s:17]3)[cH:6][n:7]1.[F:21][C:22]([O:23][c:24]1[cH:25][cH:26][c:27]([B:30]([OH:31])[OH:32])[cH:28][cH:29]1)([F:33])[F:34]>>[c:2]1(-[c:27]2[cH:26][cH:25][c:24]([O:23][C:22]([F:21])([F:33])[F:34])[cH:29][cH:28]2)[cH:3][cH:4][c:5]([CH2:8][n:9]2[c:10](=[O:20])[n:11]([OH:19])[c:12](=[O:18])[c:13]3[c:14]2[cH:15][cH:16][s:17]3)[cH:6][n:7]1

Participants

3

Reactant 2

HCID 27343864-(Trifluoromethoxy)phenylboronic acidHCID 116667261-(6-chloro-pyridin-3-ylmethyl)-3-hydroxy-1H-thieno[3,2-d]pyrimidine-2,4-dione

Product 1

HCID 115901753-Hydroxy-1-[6-(4-trifluoromethoxy-phenyl)-pyridin-3-ylmethyl]-1H-thieno[3,2-d]pyrimidine-2,4-dione

Sources & evidence

ORD record
ord-fbfe1fd84d7848a9a7834da537e3b24a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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