1-[3-(Trifluoromethyl)pyridin-2-yl]piperazine → 5-Bromo-6-trifluoromethyl-2-[4-(3-trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]-1H-benzoimidazole
Reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:5]([n:6][c:7]([Cl:9])[nH:8]2)[cH:10][c:11]1[C:12]([F:13])([F:14])[F:15].[F:16][C:17]([c:18]1[c:19]([N:24]2[CH2:25][CH2:26][NH:27][CH2:28][CH2:29]2)[n:20][cH:21][cH:22][cH:23]1)([F:30])[F:31]>>[Br:1][c:2]1[cH:3][c:4]2[c:5]([nH:6][c:7]([N:27]3[CH2:26][CH2:25][N:24]([c:19]4[c:18]([C:17]([F:16])([F:30])[F:31])[cH:23][cH:22][cH:21][n:20]4)[CH2:29][CH2:28]3)[n:8]2)[cH:10][c:11]1[C:12]([F:13])([F:14])[F:15]Participants
3
Sources & evidence
- ORD record
- ord-a12f07c8a7164fdfafd40dce5ca6bc9b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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