7-Fluoroisatin → 2-(4-chlorobenzyl)-8-fluoro-3-hydroxyquinoline-4-carboxylic Acid

HRID 1113407Notes

Reaction equation

HRID 1113407 reaction equation
[C:41]([O:42][CH2:43][C:44](=[O:45])[CH2:46][c:47]1[cH:48][cH:49][c:50]([Cl:51])[cH:52][cH:53]1)(=[O:54])[CH3:55].[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][c:7]2[n:8][c:9]3[c:10](-[c:21]4[cH:22][cH:23][cH:24][cH:25][cH:26]4)[cH:11][cH:12][cH:13][c:14]3[c:15]([C:18](=[O:19])[OH:20])[c:16]2[OH:17])[cH:27][cH:28]1.[F:29][c:30]1[cH:31][cH:32][cH:33][c:34]2[c:35]1[NH:36][C:37](=[O:38])[C:39]2=[O:40]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][c:7]2[n:8][c:9]3[c:10]([F:29])[cH:11][cH:12][cH:13][c:14]3[c:15]([C:18](=[O:19])[OH:20])[c:16]2[OH:17])[cH:27][cH:28]1

Participants

4

Reactant 3

HCID 5864187-FluoroisatinHCID 113837082-(4-Chloro-benzyl)-3-hydroxy-8-phenyl-quinoline-4-carboxylic AcidHCID 122224641-(Acetyloxy)-3-(4-chlorophenyl)-2-propanone

Product 1

HCID 114275322-(4-chlorobenzyl)-8-fluoro-3-hydroxyquinoline-4-carboxylic Acid

Sources & evidence

ORD record
ord-55598a7eff7d42a2a821892f32156855
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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