2-Amino-5-[2-fluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide → 2-[(6-{[(1,3-Dimethyl-1H-pyrazol-5-yl)methoxy]methyl}pyridin-2-yl)amino]-5-[2-fluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide
Reaction equation
[Br:21][c:22]1[n:23][c:24]([CH2:28][O:29][CH2:30][c:31]2[cH:32][c:33]([CH3:37])[n:34][n:35]2[CH3:36])[cH:25][cH:26][cH:27]1.[NH2:1][c:2]1[s:3][c:4](-[c:10]2[c:11]([F:20])[cH:12][c:13]([C:16]([CH3:17])([CH3:18])[OH:19])[cH:14][cH:15]2)[cH:5][c:6]1[C:7](=[O:8])[NH2:9]>>[NH:1]([c:2]1[s:3][c:4](-[c:10]2[c:11]([F:20])[cH:12][c:13]([C:16]([CH3:17])([CH3:18])[OH:19])[cH:14][cH:15]2)[cH:5][c:6]1[C:7](=[O:8])[NH2:9])[c:22]1[n:23][c:24]([CH2:28][O:29][CH2:30][c:31]2[cH:32][c:33]([CH3:37])[n:34][n:35]2[CH3:36])[cH:25][cH:26][cH:27]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-6a4d1852939244a4aca2cad5b965d692
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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