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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1113550Generated: October 25, 2026

Tetrahydrofuran → 4-[3-bromo-4-[(4,5-difluoro-2-nitrophenyl)methoxy]-5-ethoxyphenyl]-2-methyl-5-oxo-7-propyl-4,6,7,8-tetrahydro-1H-quinoline-3-carbonitrile

https://huagongshe.com/reaction/1113550

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantTriphenylphosphineHCID 11776—
ReactantDiisopropyl diazene-1,2-dicarboxylateHCID 75555—
Reactant(4,5-Difluoro-2-nitrophenyl)methanolHCID 57475722—
Reactant4-(3-Bromo-5-ethoxy-4-hydroxy-phenyl)-2-methyl-5-oxo-7-propyl-1,4,5,6,7,8-hexahydro-quinoline-3-carbonitrileHCID 67023381—
Product4-[3-bromo-4-[(4,5-difluoro-2-nitrophenyl)methoxy]-5-ethoxyphenyl]-2-methyl-5-oxo-7-propyl-4,6,7,8-tetrahydro-1H-quinoline-3-carbonitrileHCID 178439413—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-e04f3f7c5bfc4d6fa041ae85a3df6dfe
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)