(Iodomethyl)cyclobutane → 4-Amino-6-cyclobutylmethyloxy-7-methoxy-2-[4-(4-morpholinecarbonyl)-1,4-diazepan-1-yl]quinazoline
Reaction equation
[I:30][CH2:31][CH:32]1[CH2:33][CH2:34][CH2:35]1.[NH2:1][c:2]1[n:3][c:4]([N:15]2[CH2:16][CH2:17][N:18]([C:22](=[O:23])[N:24]3[CH2:25][CH2:26][O:27][CH2:28][CH2:29]3)[CH2:19][CH2:20][CH2:21]2)[n:5][c:6]2[cH:7][c:8]([O:13][CH3:14])[c:9]([OH:12])[cH:10][c:11]12>>[NH2:1][c:2]1[n:3][c:4]([N:15]2[CH2:16][CH2:17][N:18]([C:22](=[O:23])[N:24]3[CH2:25][CH2:26][O:27][CH2:28][CH2:29]3)[CH2:19][CH2:20][CH2:21]2)[n:5][c:6]2[cH:7][c:8]([O:13][CH3:14])[c:9]([O:12][CH2:31][CH:32]3[CH2:33][CH2:34][CH2:35]3)[cH:10][c:11]12Participants
3
Sources & evidence
- ORD record
- ord-cbc0321267694fbc8507c0fd4180212c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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