5-bromo-1H,2H,3H-pyrrolo(2,3-b)pyridin-2-one → 2-(5-bromo-2-oxo-1,2-dihydro-pyrrolo[2,3-b]pyridin-3-ylidenemethyl)-3-methyl-5-(2-morpholin-4-yl-ethyl)-5,6,7,8-tetrahydro-1H-pyrrolo[3,2-c]azepin-4-one

HRID 1113748Notes

Reaction equation

HRID 1113748 reaction equation
[Br:23][c:24]1[cH:25][c:26]2[c:27]([n:28][cH:29]1)[NH:30][C:31](=[O:33])[CH2:32]2.[CH3:1][c:2]1[c:3]([CH:21]=[O:22])[nH:4][c:5]2[c:6]1[C:7](=[O:20])[N:8]([CH2:12][CH2:13][N:14]1[CH2:15][CH2:16][O:17][CH2:18][CH2:19]1)[CH2:9][CH2:10][CH2:11]2>>[CH3:1][c:2]1[c:3]([CH:21]=[C:32]2[c:26]3[cH:25][c:24]([Br:23])[cH:29][n:28][c:27]3[NH:30][C:31]2=[O:33])[nH:4][c:5]2[c:6]1[C:7](=[O:20])[N:8]([CH2:12][CH2:13][N:14]1[CH2:15][CH2:16][O:17][CH2:18][CH2:19]1)[CH2:9][CH2:10][CH2:11]2

Participants

3

Reactant 2

HCID 155040625-bromo-1H,2H,3H-pyrrolo(2,3-b)pyridin-2-oneHCID 592500683-Methyl-5-(2-morpholin-4-yl-ethyl)-4-oxo-1,4,5,6,7,8-hexahydro-pyrrolo[3,2-c]azepine-2-carbaldehyde

Product 1

HCID 685278192-(5-bromo-2-oxo-1,2-dihydro-pyrrolo[2,3-b]pyridin-3-ylidenemethyl)-3-methyl-5-(2-morpholin-4-yl-ethyl)-5,6,7,8-tetrahydro-1H-pyrrolo[3,2-c]azepin-4-one

Sources & evidence

ORD record
ord-be5d5d6ed13341b0b39bdc768fcddb6a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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