Benzene → Tert-butyl 4-(hydroxymethyl)piperidine-1-carboxylate

HRID 1113822Notes

Reaction equation

HRID 1113822 reaction equation
[CH2:20]([Al+:21][CH2:22][CH:23]([CH3:24])[CH3:25])[CH:26]([CH3:27])[CH3:28].[H-:19].[N:1]1([C:12](=[O:13])[O:14][C:15]([CH3:16])([CH3:17])[CH3:18])[CH2:2][CH2:3][CH:4]([C:7](=[O:8])[O:9][CH2:10][CH3:11])[CH2:5][CH2:6]1.[cH:29]1[cH:30][cH:31][cH:32][cH:33][cH:34]1>>[N:1]1([C:12](=[O:13])[O:14][C:15]([CH3:16])([CH3:17])[CH3:18])[CH2:2][CH2:3][CH:4]([CH2:7][OH:8])[CH2:5][CH2:6]1

Participants

5

Reactant 4

HCID 241BenzeneHCID 166653HydrideHCID 27588121-Tert-butyl 4-ethyl piperidine-1,4-dicarboxylateHCID 16686348Bis(2-methylpropyl)alumanylium

Product 1

HCID 2764081Tert-butyl 4-(hydroxymethyl)piperidine-1-carboxylate

Sources & evidence

ORD record
ord-08f25f50c4aa48a4bd793ac1a464d22a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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