tert-Butyl [(morpholin-2-yl)methyl]carbamate → (4-{5-[1-(2,4-Bis-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-4-oxo-4,5-dihydro-thiazol-2-yl}-morpholin-2-ylmethyl)-carbamic acid tert-butyl ester
Reaction equation
[C:35]([CH3:36])([CH3:37])([CH3:38])[O:39][C:40]([NH:41][CH2:42][CH:43]1[O:44][CH2:45][CH2:46][NH:47][CH2:48]1)=[O:49].[F:1][C:2]([c:3]1[c:4]([CH2:5][n:6]2[n:7][cH:8][c:9]3[cH:10][c:11]([CH:15]=[C:16]4[C:17](=[O:24])[N:18]=[C:19]([S:21][CH2:22][CH3:23])[S:20]4)[cH:12][cH:13][c:14]23)[cH:25][cH:26][c:27]([C:29]([F:30])([F:31])[F:32])[cH:28]1)([F:33])[F:34]>>[F:1][C:2]([c:3]1[c:4]([CH2:5][n:6]2[n:7][cH:8][c:9]3[cH:10][c:11]([CH:15]=[C:16]4[C:17](=[O:24])[N:18]=[C:19]([N:47]5[CH2:46][CH2:45][O:44][CH:43]([CH2:42][NH:41][C:40]([O:39][C:35]([CH3:36])([CH3:37])[CH3:38])=[O:49])[CH2:48]5)[S:20]4)[cH:12][cH:13][c:14]23)[cH:25][cH:26][c:27]([C:29]([F:30])([F:31])[F:32])[cH:28]1)([F:33])[F:34]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-068902a14a7f4a099b958bf968dc37d7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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