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HRID11140

反应详情

EQUATION

反应方程式

HRID 11140 的结构方程式

REACTANTS

反应物

2
结构：BrB(Br)Br
HCID25134

Boron tribromide

BBr3

结构：COc1ccc2[nH]c3c(C)c(-c4ccccc4)c4c(c3c2c1)C(=O)NC4=O
HCID11843683

未命名化合物

PRODUCTS

生成物

1
结构：Cc1c(-c2ccccc2)c2c(c3c1[nH]c1ccc(O)cc13)C(=O)NC2=O
HCID11844346

未命名化合物

收率 90%

PROCEDURE

实验过程

Demethylation of (803) prepared as described in example 406 with BBr3 using the procedure described in example 69 gave (804) (90%), mp 270–280° C. 1H NMR δ [(CD3)2SO] 11.60 (s, 1H), 10.82 (s, 1H), 9.22 (s, 1H), 8.31 (d, J=2.0 Hz, 1H), 7.47–7.42 (m, 4H), 7.36–7.23 (m, 2H), 7.06 (dd, J=8.7, 2.0 Hz, 1H), 2.32 (s, 3H). EIMS found M+:342.1005. C21H14N2O3 requires: 342.1004.