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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1114185Generated: October 31, 2026

Triethylamine → (4-{8-[(Cyclopropyl-methyl-amino)-methyl]-2,2,4,4-tetramethyl-chroman-6-ylethynyl}-2-fluoro-phenyl)-acetic acid methyl ester

https://huagongshe.com/reaction/1114185

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTriethylamineHCID 8471—
ReactantTriphenylphosphineHCID 11776—
ReactantPalladium ChlorideHCID 24290—
ReactantCopper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 24350—
Reactant2-Fluoro-4-iodo phenyl acetic acid methyl esterHCID 18710225—
Reactant8-[(Cyclopropyl-methyl-amino)methyl]-6-ethynyl-2,2,4,4-tetramethyl-chromanHCID 21107250—
Product(4-{8-[(Cyclopropyl-methyl-amino)-methyl]-2,2,4,4-tetramethyl-chroman-6-ylethynyl}-2-fluoro-phenyl)-acetic acid methyl esterHCID 69074713—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-45074d2ed6cf427aa9ec753a61b255b3
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)