Methanol → 3-Oxo-3-(3-pyrimidin-2-yl-phenyl)-propionic acid tert-butyl ester
Reaction equation
[C:32]([CH3:33])(=[O:34])[O:35][C:36]([CH3:37])([CH3:38])[CH3:39].[CH3:1][O:2][C:3]([c:4]1[cH:5][c:6](-[c:10]2[n:11][cH:12][cH:13][cH:14][n:15]2)[cH:7][cH:8][cH:9]1)=[O:16].[CH3:41][OH:42].[Li:40].[n:17]1[cH:18][cH:19][cH:20][n:21][c:22]1-[c:23]1[cH:24][c:25]([C:29]([OH:30])=[O:31])[cH:26][cH:27][cH:28]1>>[C:3]([c:4]1[cH:5][c:6](-[c:10]2[n:11][cH:12][cH:13][cH:14][n:15]2)[cH:7][cH:8][cH:9]1)(=[O:16])[CH2:33][C:32](=[O:34])[O:35][C:36]([CH3:37])([CH3:38])[CH3:39]Participants
6
Sources & evidence
- ORD record
- ord-e0d76557e9344e2c859efeb7ab0e61fc
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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