Methanol → Quinacainol

HRID 1114367Notes

Reaction equation

HRID 1114367 reaction equation
[BH4-:25].[CH3:1][C:2]([CH3:3])([CH3:4])[c:5]1[n:6][c:7]2[cH:8][cH:9][cH:10][cH:11][c:12]2[c:13]([C:15]([CH2:16][CH2:17][CH:18]2[CH2:19][CH2:20][NH:21][CH2:22][CH2:23]2)=[O:24])[cH:14]1.[CH3:27][OH:28].[Na+:26]>>[CH3:1][C:2]([CH3:3])([CH3:4])[c:5]1[n:6][c:7]2[cH:8][cH:9][cH:10][cH:11][c:12]2[c:13]([CH:15]([CH2:16][CH2:17][CH:18]2[CH2:19][CH2:20][NH:21][CH2:22][CH2:23]2)[OH:24])[cH:14]1

Participants

5

Reactant 4

HCID 887MethanolHCID 923Sodium ionHCID 28123BorohydrideHCID 155816721-[2-(1,1-Dimethyl-ethyl)-4-quinolyl]-3-(4-piperidyl)-1-propanone

Product 1

HCID 55464Quinacainol

Sources & evidence

ORD record
ord-5d58318a4be242018a4dedbc67e27db1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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