Bicarbonate Ion → 3,4-difluoro-2-(2-fluoro-4-iodo-phenylamino)-N-(2-hydroxy-ethoxy)-5-[(2-propionylamino-ethoxyamino)-methyl]-benzamide
Reaction equation
[BH3:47].[C:48](=[O:49])([OH:50])[O-:51].[CH2:53]([Cl:54])[Cl:55].[F:1][c:2]1[c:3]([NH:26][c:27]2[c:28]([F:34])[cH:29][c:30]([I:33])[cH:31][cH:32]2)[c:4]([C:5](=[O:6])[NH:7][O:8][CH2:9][CH2:10][OH:11])[cH:12][c:13]([CH:16]=[N:17][O:18][CH2:19][CH2:20][NH:21][C:22]([CH2:23][CH3:24])=[O:25])[c:14]1[F:15].[Na+:52].[OH2:56].[OH:35][C:36]([CH:37]([Cl:38])[Cl:39])=[O:40].[n:41]1[cH:42][cH:43][cH:44][cH:45][cH:46]1>>[F:1][c:2]1[c:3]([NH:26][c:27]2[c:28]([F:34])[cH:29][c:30]([I:33])[cH:31][cH:32]2)[c:4]([C:5](=[O:6])[NH:7][O:8][CH2:9][CH2:10][OH:11])[cH:12][c:13]([CH2:16][NH:17][O:18][CH2:19][CH2:20][NH:21][C:22]([CH2:23][CH3:24])=[O:25])[c:14]1[F:15]Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-155d4a1c3fb2481a8a21f5759963a49e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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