Dimethyl Sulfoxide → 8-(cyclopentyloxy)-4-(3,5-dichloropyridin-4-ylamino)-3-fluoro-7-methoxy-2H-chromen-2-one
Reaction equation
[CH3:39][S:40]([CH3:41])=[O:42].[Cl:24][c:25]1[cH:26][n:27][cH:28][c:29]([Cl:32])[c:30]1[Cl:31].[H-:1].[K+:38].[NH2:3][c:4]1[c:5]([F:23])[c:6](=[O:22])[o:7][c:8]2[c:9]([O:16][CH:17]3[CH2:18][CH2:19][CH2:20][CH2:21]3)[c:10]([O:14][CH3:15])[cH:11][cH:12][c:13]12.[Na+:2].[P:33]([O-:34])([OH:35])([OH:36])=[O:37]>>[NH:3]([c:4]1[c:5]([F:23])[c:6](=[O:22])[o:7][c:8]2[c:9]([O:16][CH:17]3[CH2:18][CH2:19][CH2:20][CH2:21]3)[c:10]([O:14][CH3:15])[cH:11][cH:12][c:13]12)[c:30]1[c:25]([Cl:24])[cH:26][n:27][cH:28][c:29]1[Cl:32]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-f917b96f18c84b8abadb89db20c80bf1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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