Potassium Cation → 2-Amino-3-cyano-4-methyl-5-[3-fluoro-5-trifluoromethylphenyl]pyridine
Reaction equation
[C:26](=[O:27])([O-:28])[O-:29].[CH3:32][c:33]1[cH:34][cH:35][cH:36][cH:37][cH:38]1.[F:12][c:13]1[cH:14][c:15]([B:23]([OH:24])[OH:25])[cH:16][c:17]([C:19]([F:20])([F:21])[F:22])[cH:18]1.[K+:30].[K+:31].[NH2:1][c:2]1[n:3][cH:4][c:5]([Br:11])[c:6]([CH3:10])[c:7]1[C:8]#[N:9].[cH:39]1[cH:40][cH:41][c:42]([P:43]([Pd:44]([P:45]([c:46]2[cH:47][cH:48][cH:49][cH:50][cH:51]2)([c:52]2[cH:53][cH:54][cH:55][cH:56][cH:57]2)[c:58]2[cH:59][cH:60][cH:61][cH:62][cH:63]2)([P:64]([c:65]2[cH:66][cH:67][cH:68][cH:69][cH:70]2)([c:71]2[cH:72][cH:73][cH:74][cH:75][cH:76]2)[c:77]2[cH:78][cH:79][cH:80][cH:81][cH:82]2)[P:83]([c:84]2[cH:85][cH:86][cH:87][cH:88][cH:89]2)([c:90]2[cH:91][cH:92][cH:93][cH:94][cH:95]2)[c:96]2[cH:97][cH:98][cH:99][cH:100][cH:101]2)([c:102]2[cH:103][cH:104][cH:105][cH:106][cH:107]2)[c:108]2[cH:109][cH:110][cH:111][cH:112][cH:113]2)[cH:114][cH:115]1>>[NH2:1][c:2]1[n:3][cH:4][c:5](-[c:15]2[cH:14][c:13]([F:12])[cH:18][c:17]([C:19]([F:20])([F:21])[F:22])[cH:16]2)[c:6]([CH3:10])[c:7]1[C:8]#[N:9]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-514bca45583b48a08c44e0c8b9fefedc
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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