Carbonate Ion → tert-Butyl 2-(7-(4-(Cyclohexylmethyl)-3-(trifluoromethyl)benzyloxy)-2,3-dihydro-1H-pyrrolo[1,2-a]indol-1-yl)acetate

HRID 1114929Notes

Reaction equation

HRID 1114929 reaction equation
[C:22](=[O:23])([O-:24])[O-:25].[Cl:28][CH2:29][c:30]1[cH:31][c:32]([C:43]([F:44])([F:45])[F:46])[c:33]([CH2:36][CH:37]2[CH2:38][CH2:39][CH2:40][CH2:41][CH2:42]2)[cH:34][cH:35]1.[Cs+:26].[Cs+:27].[OH:1][c:2]1[cH:3][c:4]2[cH:5][c:6]3[n:7]([c:8]2[cH:9][cH:10]1)[CH2:11][CH2:12][CH:13]3[CH2:14][C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21]>>[O:1]([c:2]1[cH:3][c:4]2[cH:5][c:6]3[n:7]([c:8]2[cH:9][cH:10]1)[CH2:11][CH2:12][CH:13]3[CH2:14][C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:29][c:30]1[cH:31][c:32]([C:43]([F:44])([F:45])[F:46])[c:33]([CH2:36][CH:37]2[CH2:38][CH2:39][CH2:40][CH2:41][CH2:42]2)[cH:34][cH:35]1

Participants

5

Reactant 4

HCID 19660Carbonate IonHCID 104967Cesium cation2×HCID 672491474-(Chloromethyl)-1-(cyclohexylmethyl)-2-(trifluoromethyl)benzeneHCID 67249455tert-butyl 2-(7-hydroxy-2,3-dihydro-1H-pyrrolo[1,2-a]indol-1-yl)acetate

Product 1

HCID 67250595tert-Butyl 2-(7-(4-(Cyclohexylmethyl)-3-(trifluoromethyl)benzyloxy)-2,3-dihydro-1H-pyrrolo[1,2-a]indol-1-yl)acetate

Sources & evidence

ORD record
ord-0b26ba1661e94ef99d64bec32cd2bff6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

Loading…